Ukuncedisa i-Microbiome ye-Baby's Borner
Umzimba wakho wenziwe ngamaseli amaninzi. Zizonke zomzimba wakho, kungekhona ngaphakathi ngaphakathi. Ezinye zeeseli ziyingxenye yakho, ezinye iiseli ziindawo ezihlala emzimbeni wakho nasesikhumbeni sakho. Abantu abaninzi baye bakuva ukuba iibhaktheriya zihlala emanzini kwaye zisinceda sidle ukutya. Nasi umzekelo: Mhlawumbi uye wafumana ingxaki kwiibhaktheriya zakho ngento efana nesifo sesilonda kulandela ama-antibiotic.
Le yilapho i-antibiotics iphinda iphazamise ibhaktheriya efanelekileyo enceda ukugcina umzimba wethu ukhangele, ngaloo ndlela kubangela ukugqithiswa kwemvubelo.
UJoshua Lederberg uqale uchaza i-microbiome "ukuba ibonise iindawo eziphilayo zendalo, i-symbiotic, kunye ne-pathogenic microorganms ezithintela ngokwasemzimbeni indawo yethu kwaye ziye zazingagcinwanga njengezigqibo zempilo nezifo. Wadla umvuzo weNobel ngomsebenzi wakhe. Okokuqala, kufuneka uqonde ukuba ixesha elide sasicinga ukuba isibeleko sasingumhlaba ongeyinyumba kwaye oko kwatshintsha kuphela xa kukho isifo se-amniotic sac okanye uterine. Uphando olutsha kunye nezifundo zangaphambili zezilwanyana zisibonisile ukuba oku akunako ukunyaniseka, nangona singabonakali ukuba umntwana ubandakanyeka njani xa ekhulelwe okanye ukuba kunjalo. Ukuba kwenzeka, ingaba nge-placenta. Oko siyaziyo kukuba njengoko amanzi ephuka ekusebenzeni kwaye inxalenye enkulu yenqubo yenzeka xa umntwana esedlula ngesisu, umntwana uyaqhagamshelana neebhaktheriya.
Emva kokuba umntwana ezalwe, isikhumba sikhupha ukunxibelelana nomama, sinceda inkqubo iyaqhubeka. Amaninzi amaninzi azalwe ngecandelo le- laarean alahlekelwa ezi zimbini zokugqibela.
Uphando
Uphando lubonisa ukuba iintsana ezizalwe yi-laarean zithwala ukulungelelaniswa kwezinga lokunyameka, isifo se-asthma, isifo se-celiac kunye nohlobo lwe-1 lwesifo sikashukela kamva ebomini babo.
Olu phando lubonisa ukuba yinto eyahlukileyo kumxholo omncinci wegulthi edlala inxaxheba ekukhuphukeni kwezi zifo. Le yinto enye yembali yokuba kutheni ingozi yezo meko iphezulu kwiintsana ezihanjiswa yi-cearean.
Ngoko, uncedisa njani iintsana ezizalwe ngokuphelelwa yintlupheko yezinto ezincinci? UDkt. Michelle Bennett uncoma ukuthatha ama-swabs wesisu kumama kwaye uwabeke phezu komzimba kwaye emlonyeni wengane ukukunceda ukubuyisela ukulinganisela okubalulekayo kwiintsana ezizalwe yi-cearean. Olu lwazi lukwabelwana ngako kwingqungquthela yakutshanje ye-American Society ye-Microbiology ngeqela labanye oogqirha.
Ukutyalwa kweNkqubo yoMntwana
UDkt. Maria Gloria Dominguez-Bello, uprofesa onxulumene ne-Human Microbiome Programme kwi-NYU School of Medicine, wabonisa iziphumo zokuqala zophando. Unenkqubo yesinyathelo esithandathu yokwenza oko kubizwa ngokuthi inoculum okanye "ukuhluma" umntwana.
- Isampula ibhaktheriya kamama.
- Idijithi ye-gauze ifakwa kwisisini somama malunga neyure.
- Susa i-gauze ngaphambi kokuba unxweme.
- Bhengeza umntwana osanda kuzalwa kwi-gauze. (Qala ngomlomo wengane, ngoko ubuso babo, kunye nalo lonke umzimba.)
- Isampula ibhaktheriya yengane.
Kufuneka kuqatshelwe ukuba oku kuphela koomama abanentsholongwane kaGawulayo, kunye neQela B.
Nangona oku akusiyo isisombululo esipheleleyo, ibuyisela ngokukhawuleza ibhaktheriya ukusuka kumama ukuya kumntwana kwisifundo esincinci esasenziwe ngaphambili. Uphando olongezelelweyo luqhutyelwa kwaye luya kuqhubeka ngoDkt Dominguez-Bello.
Ngenxa yokuba isaphononongo akukafaneki, kodwa ezinye iingcali zenza oku xa zifunwa ngabazali okanye ngenxa yolwazi lwabo lwesifundo. Ukuba le nto ungathanda ukuyifumana emva kokuyeka kwakho, qiniseka ukuba uthethe ugqirha wakho kwaye uyifake kwisicwangciso sakho sokuzalwa .
Enye indlela yokwandisa ibhaktheriya ngokwemvelo kukuba uninzi lwekhumba ukunqamana nomama emva kokuzalwa. Nangona abaphandi bengakholelwa ukuba le nto / okanye isiphakamiso, kodwa zombini.
Imithombo:
Azad, MB, Konya, T., Maughan, H., Guttman, DS, Field, CJ, Chari, RS, Kozyrskyj, AL (2013). Gut microbiota yeentsana ezinempilo zaseCanada: iingxelo ngeendlela zokuhambisa nokutya kwabantwana kwiinyanga ezi-4. I-Canadian Medical Association Journal, 185 (5), 385-394. i-doi: 10.1503 / cmaj.121189
Abaphambuli, J., Thijs, C., Vink, C., Stelma, FF, Snijders, B., Kummeling, I., Stobberingh, EE (2006). Izinto ezichaphazela ukuBumbiswa kwe-Intestinal Microbiota kwi-Early Childhood. Izifo zengqondo, 118 (2), 511-521. i-doi: 10.1542 / iipedesi.2005-2824
IGoldberg, C. Uphando: Ngaba i-Canal-Canal Bacalia Inokuncedisa iC-Section Babies? http://commonhealth.wbur.org/2014/06/birth-canal-bacteria-c-section Ixesha lokugqibela elifikelelekile kuJulayi 18, 2015
Hyde MJ, Modi N. Imiphumo yexesha elide lokuzalwa ngenxa yecandelo lesigqirha: ityala lelingo elilawulwa ngokungalindelekanga. Hum Dev yasekuqaleni. 2012 Dec; 88 (12): 943-9.
URomano-Keeler, J., no-Weitkamp, J.-H. (2015). Iimpawu zentsapho ezichaphazela ukoloni kunye nokuphuhliswa kwe-immune. Uphando lwezilwanyana, 77 (0), 189-195. http://doi.org/10.1038/pr.2014.163
Ingoma, SJ, iDominguez-Bello, MG, & Knight, R. (2013). Indlela yokuhanjiswa kwimodi kunye nokutya kungenza njani ummandla webhakteria emathunjini omntwana. I-Canadian Medical Association Journal, 185 (5), 373-374. i-doi: 10.1503 / cmaj.130147