Kuninzi ulwazi oluphikisanayo malunga nokukhuselwa kokusebenzisa i-aspirin ngexesha lokukhulelwa. Eminye imithombo ithi inokunyusa umngcipheko wokukhulelwa kwesisu , kanti abanye bathi into eyahlukileyo. Yintoni echanekileyo? Mhlawumbi bobabini.
Indlela i-Aspirin inokunyusa ngayo ingozi yokutshatyalaliswa komtshato
Izifundo ezimbalwa zidibanise iklasi yama-painkillers eyaziwa ngokuba yi-non-steroidal anti-inflammatory drugs (NSAIDs), ezibandakanya i-aspirin kunye neyona nto yonke into ehamba phambili ngaphezu kwe-counter-counter-counter-painkiller ngaphandle kweTylenol.
Uphando lwe-2001 lwaluvela ngokufumanisa ngokukrakra ukuba ii-NSAID ngexesha lokukhulelwa zandisa ingozi yokuphuphuma kwesisu nge-80%.
Ucwaningo oluthile luka-2003 lwaluchaza iziphumo, ngokuqaphela ukuba ii-NSAID zihlobene nokukhulelwa komzimba, kanti iTylenol yayingekho, kubakho abalobi ukuba bacacise ukuba ii-NSAID ngokwazo zingabangela ukulahleka kwamathambo.
Kodwa uvavanyo luka-2006 alufumananga ubungqina bombutho phakathi kwe-aspirin ngexesha lokukhulelwa nokukhulelwa kwesisu-ngoko inyaniso ayisacacile. Kungenzeka ukuba enye into ebangela ukuba umbutho ufumaneke kwizifundo zokuqala. (Ngokomzekelo, kunokwenzeka ukuba nayiphi na imeko ibangela abafazi ukuba basebenzise ii-NSAID ziza kuba yingozi ebangela ukukhulelwa komzimba.) Okwangoku, okwangoku, oogqirha banamathele eTylenol njengendlela yokuphepha yokukhulelwa.
Indlela i-Aspirin eyayiNciphisa ngayo ingozi yokutshatyalaliswa komtshato
Kuvakala ngathi ukuphikisa ukutsho ukuba i-aspirin inokunciphisa umngcipheko wokukhulelwa kwesisu emva kokuthi kukulungele ukuphepha ukuyisebenzisa ngexesha lokukhulelwa.
Impendulo ngumlinganiselo kunye nesizathu sokusetyenziswa.
Akukho bungqina bokuba i-aspirin inenzuzo kumfazi okhulelweyo okhulelweyo, kodwa i-aspirin ye-dose ephantsi iyakunceda kubasetyhini abaye bahlaselwa ngamathambo aphindaphindiweyo ahlobene ne- antiphospholipid syndrome okanye ezinye iingxaki zokuqhawula igazi. Oogqirha babedla ukuba "umntwana" we-aspirin ngokudibanisa ne- heparin ukukhusela ukuphuphuma kwesisu kwabesetyhini kunye nale miqathango, kwaye oogqirha abathile bayancoma ama-aspirin kubafazi abathile abaye bahlaselwa ngamathambo.
Kodwa kulo hlobo lwenkqubo, umthamo we-aspirin ngokuqhelekileyo ngowesine kwento ephantsi kwiphilisi ye-painkiller, ngoko imiphumo emzimbeni inokuba yinto ehluke kakhulu kunezo idosa enkulu. (Kwaye qaphela ukuba nayiphina i-aspirin ngexesha lokukhulelwa kufuneka libe phantsi kolawulo lugqirha.)
Yintoni i-Aspirin?
I-Aspirin i-NSAID imishanguzo yokuchasa. I-Aspirin yile salicylate kunye neyeza elichanekileyo kuninzi lonke.
I-aspirin yamandla enesigqirha inikezelwa ekunciphiseni intlungu ye-rheumatoid arthritis, i-osteoarthritis nezinye iimeko ze-rheumatologic. I-aspirin engabhalwanga, okanye i-aspirin engathengwa phezu kwe-counter, isetyenziselwa ukunyanga iintlungu kunye neentlungu zemihla ngemihla, njengeentloko. I-aspirin engabonakaliyo ingasetyenziselwa ukunyanga komkhuhlane. Ngaphezu koko, i-aspirin inikwe kwakhona kubantu abaneentliziyo zentsholongwane ukukhusela ukuhlaselwa kwintliziyo ezayo. I-Aspirin isetyenziselwa ukukhusela isisu.
I-Aspirin kunye nezinye izidakamizwa ezichasene nezidakamizwa (i-NSAID) zisebenza ngokuvimbela ukusebenza kwe-enzyme cyclooxygenase. I-Cyclooxygenase ibangela ukwakheka kwe-prostaglandines eyenza ukuvuvukala, umkhuhlane kunye nentlungu. Ngaloo ndlela, i-aspirin inqanda ngokukhawuleza ukuveliswa kwe-prostaglandin kwaye ngaloo ndlela inceda ukunciphisa ukukhukhuma, umkhuhlane kunye nentlungu.
Imithombo
UJames, AH, uLR Brancazio, kunye neT. Price, "I-Aspirin kunye neziphumo zokuzala." Uvavanyo lwe-Obstetrics kunye ne-Gynecology Jan 2008. Kufumaneka ngomhla wama-26 Agasti 2008.
Keim, SA, kunye no-MA Klebanoff, "Ukusetyenziswa kwe-Aspirin kunye nobungozi bokuphuphuma komzimba." Epidemiology Julayi 2006.
ULi, uDe-Kun, uLiyan Liu, noRoxana Odouli, "Ukuboniswa kweziyobisi ezingekho phantsi kwe-steroidal ezikhuselayo ngexesha lokukhulelwa kunye nomngcipheko wokuphuphuma kwesisu: ukufundiswa kweqela labantu." BMJ 2003.
U-Nielsen, u-Gunnar Lauge, uHenrik Toft uSorensen, uHelle Larsen, kunye noLars Pedersen, "Umngcipheko wesiphumo sokuzalwa esibi kunye nokuphazamiseka kwabasebenzisi abakhulelweyo ngamachiza angenayo i-steroidal anti-inflammatory. BMJ 2001.