I-Antiphospholipid syndrome kuthetha ukuba igazi lomntu liqulethe izifo ezinxamnye neentlobo ezithile ze-phospholipids. Ukuba awuzange uthathe ikhosi yakutshanje kwi-biology yekholeji (kwaye ininzi yethu ayinayo), i-phospholipids yinto eqhelekileyo neyimfuneko yamaseli eseli kunye neeseli zezinye izidalwa eziphilayo.
Sibanzi
Xa umntu eneengqungquthela ezinxamnye ne-phospholipids, oku kunokubangela ama-clots amancinci egazini lomntu kwaye ukwandise ukutyekela kumacandelo egazi abalulekileyo, njengobunzima be-thrombosis.
I-Antiphospholipid syndrome yandisa umngcipheko weengxaki ezahlukeneyo zezempilo, ezivela kwi-stroke ukuya kwimiba ye-cardiovascular issues.
I-Antiphospholipid syndrome ingabangelwa yisifo esingenasiphelo, njenge-lupus okanye ingaba yimeko esemgangathweni ngaphandle kwesifo esaziwayo.
Isiganeko
Amaphesenti angama-2 ukuya kwimi-4 yoluntu jikelele anee-antibospholipid antibodies, kwaye ngaphezu kwesiqingatha sazo zinomdla we-antiphospholipid antibody syndrome. I-Antiphospholipid syndrome yinto ebalulekileyo malunga nama-15 ekhulwini kwabasetyhini abanobuhlungu obuphindaphindiweyo. Phantse iipesenti ezi-10 zabantu abafumene ukuba ne-antiphospholipid syndrome baya kugqitywa ukuba bane-autoimmune disease.
Ubudlelwane kwiMiscarriages Recurrent
Abaphandi baye bafumanisa ukuba ukulwa ne-antiphospholipid syndrome kunokwandisa amathuba omfazi wesifo esilaphayo. Isizathu salo asicacanga; abanye abaphandi bakholelwa ukuba i-antiphospholipid syndrome ibangela amacandelo egazi amancinci ukuvimba ukunikezelwa kwegazi kwi-placenta.
Abanye bakholelwa ukuba ukuba ne-antiphospholipid syndrome inokuphazamisa ikhono lokwenziwa kweqanda elinomhlaza lokufakelwa kwi-lining of uterus.
I-Antiphospholipid syndrome imiswe ngokufanelekileyo njengesizathu sezinto eziphambene nezidumbu ezidlulayo kodwa oogqirha abayaqinisekanga ngendima yokuba i-antiphospholipid antibodies ingadlala ekukhulelweni kokuqala.
Iimpawu
Uninzi lwabantu abane-antiphospholipid antibodies abanalo iimpawu, nangona i-disorder ingabangela igazi kunye nezinye iingxaki zempilo kwabanye abantu. Kwabesetyhini, ukulahleka kwamathambo ngokuphindaphindiweyo kunokuphela kweempawu zesifo.
Ukuxilongwa
Ukufumanisa i-antiphospholipid syndrome ingaba ngumngeni; iimvavanyo eziqhelekileyo ze- lupus anticoagulant antibodies zinokuthenjwa kwaye uvelwano luyahlukahluka kusetyenziswa i-ejenti esetyenziswe nganye kwibhribhu nganye. Ngokuqhelekileyo, xa sicinga nge-antiphospholipid syndrome njengento enokwenzeka kwiimfucuza eziphindaphindiweyo, oogqirha bafuna umntu ukuba abe neempembelelo ze-lupus anticoagulant antibodies okanye i-antiticardiolipin antibodies ngaphezu kwexesha elilodwa ngaphambi kokuba enze ukuxilongwa. Qaphela ukuba uvavanyo oluhle lwe-lupus anticoagulant antibodies alithethi ukuba umntu unesifo sengculazi.
Unyango kunye nePrognosis
Abasetyhini abaye bafumanisa ukuba bane-antiphospholipid syndrome banamava engama-70 ekhulwini lokukhulelwa okuphumelelayo kunyango, oluqhelekileyo luqukethe i-aspirin ye-dose ephantsi kunye / okanye i- injure ye- heparin . Nangona olu unyango luphucula iziphumo zokukhulelwa kwabasetyhini abane-antiphospholipid syndrome, ezi zonyango zinokunyusa amaxabiso ezinkathazo zokukhulelwa kwezi-3, kodwa kunjalo, ngoko-ke abafazi abane-antiphospholipid syndrome badinga ukuba babe neengcali ezinobungozi obuphezulu kwaye banakekelwa ngoncedo lwangaphambi kokubeleka.
Ngenxa yokuba i-antiphospholipid syndrome inokudityaniswa nezinye izixhala zempilo, ii-OB / GYN zihlala zicebisa abafazi abaye bavavanya kakuhle ukuba imeko idibene nomgqirha jikelele okanye ingcali yokujonga imeko emva kokukhulelwa. Ezinye ze-OB / GYN zicebisa malunga nokusetyenziswa kwe-hormonal contraception kubasetyhini abanembali ye-antiphospholipid syndrome nayo, ngenxa yengozi eyongeziweyo yamacandelo egazi.
Imithombo:
I-Bertolaccini, iML kunye ne-MA Khamashta, "Ukuxilongwa kwebhubheni kunye nemingeni yolawulo kwi-antiphospholipid syndrome." Lupus 2006.
U-Empson, M., M. Lassere, J. Craig, kunye noJean Scott, "Ukuthintela ukuphuphuma kwesisu ngokuphindaphindiweyo kwabafazi abane-antiphospholipid antibody okanye i-lupus anticoagulant.
I-Rai, RS "I-Antiphospholipid syndrome kunye nokuphuphuma kwesisu ngokuphindaphindiweyo." I-Journal of Postgraduate Medicine 2002.
IYunivesithi yase-Illinois - Urbana / Champaign, "Antiphospholipid Syndrom." Izibonelelo zoMonde .