Umngeni we-Clomid ngumvanyo wovalo olwenziwe ngamanye amaxesha ngaphambi kokuba unyango lwe-IVF . Uvavanyo luyaziwa nangokuthi uvavanyo lwe-citomiphene ye-citrate mngeni okanye i-CCCT.
Uvavanyo luhloselwe ukuqikelela ukuba umzimba wakho uya kuphendula ngokufanelekileyo kwizidakamizwa zokuzala kunye nokuvuselela i-ovarian. Ukususela ekubeni unyango lwe-IVF lubiza kakhulu - ngokomoya nangokwenyama - ukwenza lo vavanyo ngaphambi kokuba uqale unyango kunokukunceda ukhuphe ukudideka, ixesha elilahlekileyo kunye nokulahlekelwa yimali.
Kodwa awona wonke ugqirha wenza umngeni weComidid. Nesizathu sokuba ugqirha wakho anakho okanye angayi kululeka umngeni we-Clomid, ukuba yenziwa njani, kwaye zeziphi iziphumo zithetha.
Kutheni Kutheni Ugqirha Wakho UnokuLawula i-Clomid Challenge Test
Uvavanyo locelomngeni lwe-Clomid lujoliswe ekuhloleni umgangatho kunye nobungakanani bamaqanda kuma-ovari. Xa ugqirha uthetha malunga nokuvavanywa kweendawo zokugcina ii-ovari, oku kuthetha oko. Kuvavanya indlela enempilo kunye nendlela amaqanda akho aninzi ngayo.
Uvavanyo locelomngeni lwe-Clomid luye kuphela lweendlela ezininzi zokuvavanya ama-ovarian reserve, kwaye akubona wonke umntu ovuma ukuba yinto ekhethekileyo. (Oku ngakumbi kwizantsi apha)
Ezinye iikliniki zenza inselele yeComid kuzo zonke izigulane zazo, kodwa ininzi kuphela ukuvavanya ukuba iimvavanyo ezithile zidibene. Ugqirha wakho unokuyalela umngeni weComidid ukuba:
- Uphelile kwiminyaka ethile. Ngokuqhelekileyo ngaphezu kweminyaka engama-37, kodwa oogqirha abathile bavavanya uvavanyo kubo bonke abafazi abangaphezu kwama-35.
- Amazinga akho e-FSH aphezulu. Icandelo lovavanyo lwakho lokuqala lokuzala luquka uvavanyo lwe -FSH oluphantsi , olujongene namanqanaba akho e-FSH hormone ngosuku lwesithathu umjikelezo wakho wokuya esikhathini. Ukuba iziphumo zakho ziphezulu okanye ziphezulu, ugqirha wakho unokufuna ukwenza umngeni weComid.
Abanye oogqirha baya kwenza uvavanyo lwe-Clomid yocelomngeni ngexesha lokunyanga kweComid. Konke okufunekayo kukuba umsebenzi wegazi rhoqo kwaye mhlawumbi i-ultrasound.
Uninzi lwexesha, nangona kunjalo, iklinikhi yenza inselele yeComid ngaphambi kokuqala unyango lwe-IVF kunye namaxesha athile ngaphambi kokuba unyango lwe-IUI.
Ukuba izidakamizwa zokuzala ngexesha le-IVF azikhuthazi amaqanda akho ngokufanelekileyo ukwenzela ukuvelisa amaqanda anele ukufumana, umjikelo wakho uya kukhutshwa.
Yonke imali esetshenziselwa unyango kuloo phuzu iya kulahleka, ingakhankanyi inkcazo yoxinzelelo.
Uvavanyo locelomngeni lwe-Clomid lusetyenziselwe ukuchonga ukuba ngaba ii-ovari zakho ziyakwazi ukuphendula kakuhle phambi kokuba uchithe ixesha kunye nemali unyango.
Kutheni Kutheni Ugqirha Wakho Awuyi kuLawula i-Clomid Challenge Test
Uphando lubuze ukuba ngaba i-Clomid Challenge iyakwazi ukuqikelela ukuhluleka kwe-IVF. Nangona ezinye iingcaphephe zifumene ukuba iCCCT ikwazi ukuxela ubungako bempumelelo ye-IVF, ezinye iifundo zifumene uvavanyo ukuba lube luquka okanye aluhambanga njengenye i-ovarian testings testings.
Ngokomzekelo, uphando oluthile lufumene ukuba uvavanyo lwe-FSH lwe-basal - oluye luvavanyo lwegazi ngosuku lwesithathu lomjikelezo wakho - luchanekile njengengxaki yeComomid ekuchazeni ukuhluleka kwe-IVF.
Ezinye iziphumo ziye zafumanisa ukuba inani le-antral follicle (ARC) lichanile ngokuchanekileyo ekuqikelelweni kweendawo zokugcina ii-ovari ngaphezu kocelomngeni lwe-Clomid. Isibalo sokulandelelana kwesigxina sifaka i-ultrasound yangaphandle kwaye ayifuni ukuthabatha nayiphi na imithi.
Ngoxa uvavanyo lwe-Clomid mngeni lufuna ukuba uthathe i-Clomid-isilwanyana esinemiphumo emibi kunye neengozi-Ukuhlolwa kwesiseko se-FSH kunye nenani lentambo ye-antral ayingozi kakhulu.
Omnye umba kunye nenselele yeComidid kubangele uxhalaba kwizigulane ezinokuvavanya, kwaye olu xhalaba lungafanele lube lufanelekile neziphumo ezinikezayo (okanye aluniki.)
Ngenxa yezi zizathu, abanye oogqirha bakhetha ukungayenzi uvavanyo lwemibuzo ye-Clomid.
Uvavanyo lweComid Challenge lwenziwa njani?
Njengamaxesha onke, kufuneka ulandele imiyalelo enikwe ngugqirha wakho.
Ngokuqhelekileyo, uvavanyo lwe-Clomid mngeni lufuna ukuba unayo igazi lokudweba ngomhla we-2, 3 okanye 4 wesijikelezo sakho sokuya esikhathini. Oku kuya kuthunyelwa kwibha, kwaye baya kujonga amazinga akho eFSH kunye ne-estradiol.
Emva koko, kwiintsuku 5, 6, 7, 8, no-9, uya kuthatha 100 mg ye-clomiphene citrate.
Ngokuqhelekileyo, oku kuya kubakho iipilisi ezi-50 mg ezithathwe ngexesha elifanayo, kodwa zibuze ugqirha ukuba awuqinisekanga.
Emva koko, ngomhla we-10, uya kuba nelinye igazi ukudweba ukujonga amazinga akho eFSH kwakhona.
Abanye oogqirha banquma ukuba i-ultrasound yangaphakathi ibalekele kwaye ilinganise nayiphi na ipollicles ekhulayo kuma-ovari.
Imiphumela
Unokufumana iimpembelelo ezifanayo njengoko umntu ethatha iCommid yokunyanga . Enyanisweni, ugqirha wakho angenza uvavanyo ngexesha lomjikelezo ukuba baphatha nawe ngenxa yokungabikho.
Ukwahlukana kuphela phakathi kokuphathwa kunye neComomid yokugcoba kunye nokuba novavanyo lwe-Clomid mngeni unomsebenzi wegazi ngaphezulu ngexesha lomngeni.
Nangona kunjalo, ungacingi ukuba usuqedile uvavanyo lwe-Clomid mngeni ngenxa yokuba uthathe iComomid ngaphambili. Ugqirha wakho angenako ukwenza umsebenzi wegazi okongeziweyo okanye i-ultrasounds ngelo xesha.
Thetha ugqirha wakho malunga nayiphi na impawu eqhelekileyo enayo ngexesha lovavanyo.
Kwakhona ugcine engqondweni ukuba ukuba unesondo esingakhuselekanga ngexesha lomngeni we-Clomid, unokukhulelwa kwaye usengozini yokukhulelwa amawele .
Isiphumo esiqhelekileyo sovavanyo lwe-Clomid Challenge Test
Iziphumo eziqhelekileyo zihluka ngokukodwa kwibhuyibhile kwibhuyibhile, ngoko kuya kufuneka ukuba uxoxe ngeziphumo zakho kunye nogqirha wakho ukuba wazi ukuba iziphumo zakho zijongwa ngokuqhelekileyo okanye kungekho kwiklinikhi yazo.
Ngokomnye uphando, ukuba nenqanaba le-FSH phakathi kwe-3.1 no-10.0 I-I / I ithathwa njengoluhlu oluqhelekileyo.
Inqanaba eliphezulu le-FSH lalibhekwa likhulu kune-10.0 IU / I, kunye ne-24 IU / I ibe yinqanaba eliphezulu le-FSH.
Iziphumo zakho zeFSH ziphezulu ngexesha lomngeni weComidid, unyango oluncinci lwe-IVF luya kuphumelela kuwe.
Kwisifundo esinye, i-76% yabasetyhini abaye bahamba nomngeni we-Clomid babecingwa ukuba baneziphumo eziqhelekileyo kunye neendawo zokugcina ii-ovarian, kunye ne-24% yabasetyhini "abangaphumeleli" umngeni weComidid. Olunye uphando lufumene ipesenteji encinci yabasetyhini abafanelekanga kwi-IVF unyango emva komngeni we-Clomid.
Iinqanaba zase-Estradiol zikwaqwalaselwa ngethuba lomngeni weComid. Isiphumo esiqhelekileyo seSuku 3 sinanto phakathi kwe-25-75 pg / ml.
Qaphela ukuba ukufumana isiphumo esiqhelekileyo ngexesha lomngeni we-Clomid akuthethi ukuba i-IVF izakukhulelwa okanye ukuba ii-ovari zakho ziphendule kakuhle kwizidakamizwa zokuzala.
Ngolu vavanyo, umphumo kuphela onokuthi uthethe umphumo ombi.
Ukwenza kakubi kwi-Challenge ye-Clomid kwandisa iingxaki ezingenakuphumelela kwi-IVF.
Ukuqhuba kakuhle kwi-test ye-Clomid yovavanyo mingeni akuthethi kakhulu malunga nokuba uya kukhwela unyango lwe-IVF.
Yintoni eyenzekayo emva kokusilela kweComid Challenge Test?
Ngokuqhelekileyo, ukuba iziphumo zakho azilungile ngexesha lovavanyo lwe-Clomid mngeni, ugqirha wakho uya kukuxelela ukuba iziphumo zakho zokuphumelela ngonyango lwe-IVF ziphantsi.
Uninzi lweeklinikhi ziza kuthatha ingqalelo ezinye iziphumo zokuvavanya izilwanyana kunye neempembelelo zakho ze-Clomid. Khumbula ukuba akusiwo wonke umntu ovuma ukuba iCCCT iyona vavanyo elona lifanelekileyo leendawo zokugcina ii-ovari.
Isinyathelo esilandelayo siya kuxhomekeka kwigqirha yakho kunye nawe.
Ezinye iiklinikhi zenqaba ukunika unyango lwe-IVF kwabasetyhini abangaphumeleli inselele yeComomid. Okanye, baya kunikezela kuphela umguli we-egg donor IVF.
Ngomnikeli weqanda, iindawo zokugcina ii-ovarian ezingafanelekanga.
I-IVF kunye ne-egg donor inezinga eliphezulu lokuphumelela kwezinga, nemiphumo eyimpumelelo engcono kunabesifazana abaneendawo ezifanelekileyo zokugcina ii-ovari ezihamba nge-IVF. Kodwa kubiza, kwaye akusiyo wonke umntu ofuna ukusebenzisa umxhasi weqanda.
Umxhasi we-IVF uyimfuneko yokuqwalasela, kodwa ugqirha wakho akakwazi ukuthetha. Umxhasi we-IVF unesixabiso esincinci kunomsikeli weqanda i-IVF kwaye mhlawumbi engabizi ngaphantsi kwe-IVF yendabuko. Ngoko qiniseka ukubuza malunga nalo.
Ukuba awufuni ukuya kwindlela yokunikela, kunye neklinikhi yakho ikujike kwaye iyenqabe ukukuphatha, khumbula ukuba oku kungabikho ngenxa yokuba abafuni ukuphazamisa amazinga abo okuphumelela kwe-IVF.
Ezinye iikliniki zijolise ngakumbi ekuncedeni abafazi abaneendawo zokugcina ii-ovarian. I-egg donor IVF ingaba yinto ekhethekileyo kuwe, kodwa kungcono xa usebenza nodokotela owaziyo nemingeni yakho yokuzala.
Ukuba ufuna ukuqhubeka ne-IVF yendabuko, ukwazi ukuba iimpumelelo zakho ziphantsi, abanye oogqirha banokukulungele ukunikezela unyango.
Enoba le nto inomdla kakhulu, nangona kunjalo, umcimbi wengxoxo.
Ukufumana imbono yesibini ngaphambi kokutyhala ixesha lakho, imali, kunye neemvakalelo kunyango mhlawumbi yindlela efanelekileyo yokuyithatha.
Imithombo:
I-Adibi A, iMardanian F, Hajiahmadi S. "Ukuthelekiswa komthamo we-Ovari kunye ne-Antral follicle kubalwa novavanyo lwe-Endocrine ngokuchazwa kwempendulo kwi-ovulation protocoles." I-Adv Biomed Res. 2012: 1: 71. i-doi: 10.4103 / 2277-9175.102975. Epub 2012 Oktobha 31. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544132/
Broekmans FJ, Kwee J, Hendriks DJ, Mol BW, Lambalk CB. "Ukuphononongwa ngokuchanekileyo kweemvavanyo ukuqikelela ukugcina i-ovarian reserve kunye ne-IVF". 2006 NgoNovemba-Dec; 12 (6): 685-718. Epub 2006 u-Agasti 4. http://humupd.oxfordjournals.org/content/12/6/685.long
I-Csemiczky G, i-Harlin J, iFried G. "Amandla okuqhelisela ukuhlolwa komngeni we-citomiphene yokungaphumeleli kwonyango lwe-vitro fertilization." I-Acta Obstet Gynecol Scand. 2002 Oct; 81 (10): 954-61. http://www.ncbi.nlm.nih.gov/pubmed/12366487
Hendriks DJ, Mol BW, Bancsi LF, te Velde ER, Broekmans FJ. "Ukuhlolwa kovavanyo lomngeni we-citomiphene ukuchazwa kwempendulo ye-ovarian ephosakeleyo kunye nokungabikho komzimba kwizigulane ezithotyelwayo kwi-vitro fertilization: ukuhlolwa ngokufanelekileyo." UFertil Steril. 2006 Oct; 86 (4): 807-18. Epub 2006 Sep 7. http://www.ncbi.nlm.nih.gov/pubmed/16962116
I-Ramalho de Carvalho B, iGomes Sobrinho DB, i-Vieira AD, i-MP ePhalamende, i-Barbosa AC, i-Silva AA, i-Nakagava i-HM. "Uvavanyo lwama-ovarian lokuhlola uphando." I-ISRN Obstet Gynecol. 2012; 2012: 576385. i-doi: 10.5402 / 2012/576385. Epub 2012 Jan 26. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302183/