I-acid ye-folic, ngamanye amaxesha abizwa ngokuba yi-vitamin B-9 okanye i-folate, i-vitamin e-soluble yamanzi kwiintsapho ze-B ezinzima. Wonke umntu udinga ukutya okubandakanya i-aclic acid, kungakhathaliseki ukuba ngaba abakhulelwe okanye bengenayo, njengokuba ukungazinzi komntu kungabangela iingxaki zempilo ezinzulu. Nangona kunjalo, ukutyiwa okwaneleyo kwe-acid e-folic kubhekwa ngokubalulekileyo kubasetyhini bexesha lokuzala.
Abaninzi kwisithathu kwabasetyhini baseMntla waseMerika abanako ukufumana i-folic acid efanelekileyo kwiidlo zabo, naphezu kokukhutshwa kwemveliso yengqolowa kunye nesondlo.
Iifayile ze-Folate neNeural Tube Defects
Ingxabano enamandla kunazo zonke abafazi abakhulelweyo abafuna i-folic acid supplements bavela kwi-tie phakathi kokutya okwaneleyo kunye nokunciphisa umngcipheko wokuba nomntwana onesiphene se-neural tube . Iziphene ze-Neural tube ziyinxalenye yokukhubazeka kokuzalwa komntwana okuchaphazela ingqondo kunye nomgudu womgudu, oqhelekileyo u-spina bifida kunye ne- anencephaly . Iingxaki ze-Neural tube zingakhubaza okanye zibulale ngisho nosana olusakhulayo.
Kukho iqela elikhulu lophando olubonisa ukuba omama banesidlo esaneleyo se-acid e-folic ngaphambi kokukhulelwa banama -50 ekhulwini ukuya kuma-70 ekhulwini kumngcipheko omncinci wokuba ne-baby ne-neural tube defects. I-tube ye-neural ivala ngomhla wama-28 emva kokukhulelwe, okanye malunga neeveki ezimbini emva kwexesha elilahlekileyo, ngoko ke kwiimeko ezininzi, ixesha elibalulekileyo linokudlula ngaphambi kokuba ufunde ukuba ukhulelwe.
Ngenxa yokuba ukukhulelwa okuninzi akucetywanga, i-CDC incomela ukuba abafazi abaneminyaka yokubeletha baqiniseke ukuba badle ubuncinane ubuncinane be-400 micrograms (mcg) ye-folic acid imihla ngemihla-kwaye abo baceba ukukhulelwa kufuneka baqinisekise ukuba bafumana loo mali ubuncinane Kwiinyanga ezintathu ngaphambi kokukhulelwa. Eli nqanaba lokungeniswa lingafumaneka ngokulula ngokuthatha i-vitamin (okanye enye i-multivitamin ubuncinane ubuncinane be-400 mcg ye-folate), kodwa kunokwenzeka ukuba ufumane i-folic acid eyaneleyo ekudleni kwakho ngaphandle kokuncedisa ukuba unononophelo ukhetha i- folate- ukutya okucebileyo .
Ukuba unomntwana onokukhubazeka kwesikhumba se-neural esikhathini esidlulileyo, ugqirha wakho unokucebisa ukuba uthathe ngaphezu kwe-400 mcg ye-folate ngosuku ngemini ngaphambi kokuba ukhulelwe kwakhona. Xoxa nodokotela wakho malunga nokuba kunengqondo kwiimeko zakho.
Ezinye iinzuzo ze-Folic Acid
Nangona ixesha elibalulekileyo leetyala ze-neural tube phambi kokuba ufumene ukhulelwe, oko akuthethi ukuba i-folic acid ayinalutho ukuba sele ukhulelwe. Ihlala isisombululo esibalulekileyo sokwahlukana kweeseli kunye nokukhula, okwenza izizathu zokuzithatha ngexesha lokukhulelwa konke kubonakala.
Ukongezelela, kukho ubungqina bokuba i-folic acid inokunciphisa umngcipheko wezinye iziphoso zokuzalwa kunye nokuba ama-mama anama-folic acid aphantsi ayenokuba nomngcipheko ophezulu wokukhulelwa kwesisu , ukuphazamiseka kwamaplaza kunye nokuhanjiswa kwangaphambili- mhlawumbi ngenxa yobudlelwane phakathi kwezantsi folic acid kunye namazinga ase- homocysteine .
Kodwa Ingaba Ingozi Eninzi Ingozi?
Akukho mpela umda ophezulu owaziwayo malunga nokuba i-folic acid ikhuselekile kangakanani, kodwa ngamanye amaxesha iingcali zicebisa abafazi ukuba bagcine i-folic acid ngaphantsi kwe-1000 mcg ngosuku, ngenxa yemibandela embalwa yokuba ukuxhaswa kwe-folic acid kunokugqithiswa ngokunyuka umngcipheko wesondo kunye nezinye iingxaki zokuphefumula umntwana.
Kukho ubungqina obuninzi ngakumbi ekusebenziseni ukuxhaswa kwe-folic acid ngaphezu kobungqina obuchasene nayo, kodwa ezi ziphumo zibonisa ukuba ukugcina ngaphakathi kwemida ephakanyisiweyo ingaba yinto efanelekileyo.
Imithombo:
Callaway, Leonie, uPaul B. Colditz noNicholas M. Fisk. Ukuxhaswa kwe-Folic Acid kunye nokuzalwa kwangaphambili kwangaphambili: Ukongeza iGrist kwiMill? "I- PLoS Med 2009 ngoMeyi; 6 (5): e1000077.
Amaqiniso Nge-Acrylic Acid. CDC. http://www.cdc.gov/ncbddd/folicacid/about.html
Håberg, SE, SJ London, H Stigum, P Nafstad naseW Nystad. "I-folic acid supplementary in pregnancy and childhood respiratory health." IiNqoloba zeZifo ebuntwaneni ngo- 2009; 94: 180-184.
Scholl, Theresa O. noWilliam G Johnson. "I-acid ye-folic: impembelelo kwisiphumo sokukhulelwa." Am J Clin Nutrition. 2000; 71 (suppl): 1295S-303S.
USherwood, uKelly L, uLisa A. Houghton, uValerie Tarasuk noDeborah L. O'Connor. "Omnye-Okwesithathu kwabafazi abasetyhini nabalumkileyo abakwaziyo ukudibana neentlanga zabo ezifunekayo kwiSondlo eziZodwa ngokusekelwe kwiNqanaba eliMiselweyo loLungiso lweFolic Acid." J. Nutriti. 2006 136: 2820-2826.