Isikhathi sakho sokuya esikhathini: Indlela iNkqubo yokuZalwa koBhinqa isebenza ngayo ngokwenene

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Ngaphambi Kwangaphambi Kokuya Kwisini

Inkqubo yokuzala isithintelo kakhulu, kwaye yonke into isebenze ngokufanelekileyo, amahomoni amaninzi, izigulane kunye nezitho kufuneka zenze imisebenzi yazo ngokufanelekileyo, ngexesha elifanelekileyo. Emva kokuba uqonda indlela inkqubo yokuzala isebenza ngayo, kulula ukuqonda ukuba izinto zingahamba njani. Yimangalisa impela ukuba izinto zihamba ngqo, zinikwa nzima ukuba yonke inkqubo!

Kwakhona, ukuqhelana nendlela inkqubo yokuzalisa ngayo inokukunceda ukuba uqonde ukuba kutheni ukunyanga ezithile zonyango zenziwa ngamaxesha athile.

Ukuziqhelanisa neenkqubo zokuzala kunokukunceda uqonde indlela yokukhulelwa ngokukhawuleza , ngokukunceda ixesha lokulala ngesondo .

Ngaphambi Kwangaphambi Kokuya Kwisini

Sivame ukucinga inkqubo yokuzala njengento esebenza kwimijikelezo yenyanga, nje ngomjikelezo wethu wokuya esikhathini. Nangona oku kunyanisweni, kunzima kakhulu kunoko.

Iqanda onokuyivula le nyanga sele lilungele ngaphakathi kwintolongo kwiintsuku ezi-290 ezedlulileyo, malunga neenyanga ezili-9. Enyanisweni, iqanda liye lajikeleza njengeqanda elidala ngenxa yokuba ubengumntwana ongaphantsi kwesisu somama wakho.

Xa uhlala nje unye, malunga namaviki angama-12, i-ovaries yakho iqulethe ama-egg angama-6 ukuya ku-7-awona uninzi oya kuba nawo ebomini bakho. Ngexesha ozalelwe ngalo, kwakukho izigidi ezingama-2 kuphela ezishiywe amaqanda, kwaye ngeli xesha uqala ukuhamba kwimihla yokuya esikhathini, ama-ovari akho aphethwe ngama-500,000 kuphela.

Yintoni eyenzekayo kuzo zonke izigidi zeeqanda ezinokubakho? Ziya kuphi na?

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I-Great Egg Race: Indlela iifolisi ezikhula ngayo kwi-egg eveziwe

Ezi zigidi zamaqanda angamaqabane ayenziwa ngamaqanda akho xa usemncinci ziqulethwe kwizinto ezibizwa ngokuba yizinto eziphambili ze-follicle, kwaye ezininzi zazo ziyafa njengoko ixesha lidlulayo .

Xa kufika ixesha lokuba umjikelezo wokuqala wokuya esikhathini, iqela lokuqala lamanye ama-Follic fols asele aqala "ukuvuka".

Njengoko bevuka, kukho uhlobo lokuncintisana phakathi kwabo njengoko bekhula.

Ngenyanga nganye ezinye zezi follicle eziphambili ziyayeka ukukhula, kunye neyona nto ihamba phambili yeqela elihamba phambili ngenyanga ezayo yokukhula. Kule qela, kuphela iqela elikhethiweyo liya kuba yimiba yezinto eziphambili, ize ibe yinto eyaziwa ngokuba yimibuzo yesibini.

Kufana nje nomdlalo we-follicle marathon ukubona ukuba ngubani oya kuba liqanda eliphumelelayo.

Ekugqibeleni, kuphela enye (kunye ngamanye amaxesha) kwale follicle ibe liqanda elivuthiweyo ukuze likhutshwe.

Kodwa yintoni ebangela ukuba le follicle ibalekele kwindawo yokuqala?

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Ukufumana iRigor Egg Great Uqalise

Ukufumana umqhudelwano weqanda lomdlalo weqanda kufana nokugqithwa komkhosi kunye kunye.

Kuze kubekho iipolisi eziphambili kwaye ziba yinto eyimpumelelo kunye neyesi-follicle yesibili, uhlanga luqhubela phambili ngaphakathi kwi-ovary.

Kodwa xa kufika ixesha lokuba iqela lee-follicles ezikwinqanaba lize liba liqanda elivuthwe, amahomoni avela ngaphandle kwe-ovary adlala indima ebalulekileyo.

I-hypothalamus gland, ekhoyo kwingqondo, iqala umqhubi okhuphayo ngokukhupha i-gonadotropin-release hormone, okanye i-GnRH. Oku kwenzeka ngosuku lokuqala lwenyanga yakho.

Le hormone ibonisa i-pituitary gland ukuvelisa ama-hormone amabini, i-hormone evuselela i-follic, okanye i- FSH , kunye ne-hormone ye-luteinizing, okanye i-LH.

Nangona i-pituitary gland ivelisa zombini i-FSH ne-LH, igcina ubuninzi be-LH kamva. Ngexesha leentsuku zokuqala zomjikelezo wakho wokuya esikhathini, yi-FSH ekhutshwa kakhulu.

Oku kukuqala kwento eyaziwa njengesigaba sesilandela somjikelezo wesini.

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IsiGaba seNkcazo seNgqungquthela yokuHamba

Ngexesha lesiganeko sokulandelelana kwimijikelezo yokuya esikhathini, malunga neetlanu eziyisixhenxe ezilandelanayo kwi-ovary (kunye ngamanye ama-ovari) ziqala ukugijima ukuya kumgca wokugqibela.

Ukukhula kwabo kukhuthazwa yiHS hormone. Igama linikezela - i-FSH iyimiphunga ye-follic-stimulating hormone, okanye ngamanye amagama, i-hormone evuselela i-follicles ukuba ikhule.

Njengoko iifolli zikhula zikhulu, ziqala ukukhulula i-hormone estrogen. Njengoko i-estrogen ihamba ngegazi, yenza indlela yayo yokubuyela kwintsimbi ye-pituitary, ebangela ukuba intsimbi iyancipha ukuveliswa kwe-FSH.

Oku kuthiwa yi-negative-feedback - njengoko i-estrogen iphakama, i-FSH iyancipha.

Ekugqibeleni, enye (kunye ngamanye amaxesha) e-follicles ibe yintolisi ephezulu. I-follicle ephezulu ikhupha ixabiso le-estrogen egazini.

Xa ulandelelwano lufikelela kwizigaba zokugqibela zokukhula, umjikelezo ongezantsi-mpendulo uyatshintsha kumjikelezo wempendulo. Oku kuthetha ukuba ukunyuka kwe-estrogen kukhokelela ekukhuleni kwe-FSH.

Ngamanye amazwi, amanqanaba aphezulu e-estrogen ngokukhawuleza abangela i-spike kwi-FSH, uhlobo olufana nokugqibela kweqanda kwiqanda elikhulayo.

Kodwa emva kokugqibela kwe-FSH sprint, i-pituitary gland iyanciphisa ngokukhawuleza imveliso ye-FSH.

Oku kuqalwe kwesigaba esilandelayo somjikelezo wesini, esaziwa njengesigaba se-ovulatory.

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Isigaba se-Ovulatory seNkqubo yokuHamba

Njengamanqanaba e-FSH aphantsi, i-follicle ephezulu iyaqhubeka ikhula kwaye ikhulula i-estrogen. Ezinye iifollic ezingazange ziphumelele umncintiswano ziyafa.

Ngoku, kungomdla weqanda okanye amaqanda (kwimeko yamawele angafani).

I-estrogen ekhutshwe yi-follicle evuthiweyo yenza okungaphezulu nje kokuvala ukunikezelwa kwe-FSH kwi-pituitary. I-estrogen ikwaxanduva lokuvuselela i-endometrium, okanye ibhande le-uterus, ukuze likhule.

I-endometrium ikhula ukusuka malunga ne-0.5 millimeters ngobunzima ekuqaleni komjikelezo wakho, ukuya kuma-5,5mimitha ubukhulu ekupheleni.

I-hormone ye-estrogen nayo ixanduva lokunyuka kwebhola lomlomo wesibeleko kunye nokutshintsha kwimeko yakho yomlomo wesibeleko , ukulungiselela izimo eziya kulungele ukuthutha kunye nokwamkelwa kwesidoda kwiqanda. Kwakwandisa inqanaba lakho lesifiso sesini , indlela ye-biology yokukunceda ixesha lesini ngokukhulelwa.

Xa ipolisi ephezulu ikulungele ukukhutshwa, amanqanaba e-estrogen. Olu phuhliso lubangela ukuba i-pituitary gland ibe yintsholongwane kwi-hormone GnRH, ekhokelela ekukhutshweni kwe-LH kwi-grey pituitary.

Ukunyuka kwi-LH kubonisa ukuba ubugqwetha ukukhulula iqanda. Ngomhla wokunyuka kwakho kwe-LH, uza kuba ne-mucus yomlomo wesibeleko kunye nesimo sakho somlomo wesibeleko siya kuphakama, kunye nomlomo wesibeleko ovulekileyo kunye ovulekileyo. Yiyo le nto eyenza ukuba iikiti zokucwangcisa i-ovulation ikuncede.

Kwiiyure eziyi-24 ukuya kwii-48 ze-LH, i-follicle ehamba phambili kunye neqanda eliphumelelayo ekugqibeleni likhutshwe kwinkqubo ebizwa ngokuba yi-ovulation.

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IsiGaba seLuteal seNyanga yokuHamba

Emva kokuba iqanda likhutshwe, isigaba sokuqhawula umjikelezo wesini siqala.

Iqanda elikhishiwe linamahora angaba ngu-24 ukufumana isilwanyana ngokulinda isibindi, kwaye oku kuya kwenzeka njengokuba iqanda lingena kwi-tube fallopian. Ukuba ubulele ngesini kwiintsuku ze-LH, i-sperm kufanele ibe khona, ilinde ukubulisa iqanda elivuthwe.

Okwangoku, i-hormone ye-LH ibangela ukuba i-follic rupture ibe yinto eyaziwa njenge-corpus luteum. Umsebenzi we-corpus luteum ukugcina ukhulula i-estrogen kwaye ukhulule i-hormone entsha, i-progesterone.

I-Estrogen isikhuthaza ukuba umlenze wesibeleko uqhubeke ukhula, ngelixa i-hormone progesterone inceda umgca we-uterus uyamkela iqanda elichumayo.

Iprogesterone ijongene nalao mpawu yokukhulelwa okukhuselekileyo enokubandezela abaninzi phakathi kweveki ezimbini silinde .

I-progesterone yehommone nayo ibangela ukwanda kancinci kumbindi wakho womzimba, oko kukubangela ukutshintsha kweqondo lokushisa ozibonayo ukuba utshintshisa izinga lokushisa lomzimba wakho .

Ubomi be-corpus luteum bufutshane, nangona kunjalo.

Ukuba iqanda litsalwa, i-embryo iya kukhupha iHHG, i-chorionic gonadotropin. iHCG iyafana ne-hormone LH, kwaye igcina i-corpus luteum ephilileyo, ivelisa i-estrogen kunye neprogesterone ukuze igcine ukukhulelwa.

Kodwa, ukuba iqanda lingaqhelwanga, i-corpus luteum iqala ukutshatyalaliswa iintsuku ezintathu ngaphambi kokuba ufumane ixesha lakho. Ama-hormone e-estrogen kunye neprogesterone ahla, okwenza i-endometrium idibanise kwaye ekugqibeleni iholele ekuya esikhathini.

Ngelixa sisalila ngenye inyanga engaphumelekanga, kunjalo, imizimba yethu ayichitha ixesha kunye namaqela onobubele. Usuku lwakho ixesha eliqala ngalo ngumhla apho i-hypothalamus iqala ukukhulula i-GnRH kwakhona, ukuqala enye imarathon kwiqela elilandelayo lemibuzo yokulinda.

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Unyango lwezoNyango kunye nexesha lakho lokuya esikhathini

Ngoku ukuba uyayiqonda inkqubo yokuzala, kuya kuba lula ukuqonda indlela kunye nantoni yokuhamba kwemizila.

Ngokomzekelo, ngoku uyazi ukuba kuthatha ixesha elide - ngaphezu kweenyanga ezili-9 - ukuba ulandelelwano olusanda kufakwa ukuze ulungele uhlanga ngokubhekiselele kwi-ovulation. Yingakho ezinye iinguqu zokuphila zingathatha ixesha lokwenza umehluko ekuzaleni kwakho.

Kwakhona, izidakamizwa ezifana ne-metformin, isicatshulwa se-insulin yokuxhatshazwa ngamanye amaxesha esetyenziselwa ukunyanga ukungabikho komntwana kwabasetyhini abane- PCOS , inokuthatha iinyanga ezi-6 ukusebenza.

Iziyobisi

Unokuqonda kakuhle ukuba kutheni uthatha izidakamizwa ezithile zokuzala ngexesha elithile kumjikelezo wakho. Umzekelo, iComomid ithathwa ngexesha lokuqala kwinqanaba lomlandelelwano lomjikelezo wakho, kuba lixesha apho iifolli zikhula kwaye zilungiselela ukuvuthwa.

Ngexesha lomjikelezo we- IVF , ungathatha oko kwaziwa ngokuba ngumphikisi we- GnRH ngeveki ngaphambi kokuba ulindele ixesha lakho. Umnquli we-GnRH ukhusela i-pituitary gland ukukhupha i-LH ne-FSH, ukuze ugqirha wakho angakwazi ukulawula umjikelezo.

Izidakamizwa ezifana ne- Gonal-F kunye ne-Follistim zenziwe ngama-hormone e-FSH. Ngoku uyazi ukuba i-FSH yi-hormone ejongene nokukhuthaza ukukhula kobugqwetha kwii-ovari.

Izidakamizwa ezifana ne-Ovidrel, edlalwa ngokuba yi-"trigger shot", ithatha indawo okanye iphakamisa ukunyuka kwe-LH okubangela ukukhula kokugqibela kweqanda kwaye ekugqibeleni i-ovulation.

Kwaye emva kokuvuthwa, i-progesterone isongezelelo. Ngexesha le-IVF, xa amaqanda athatyathwa, i-follicle isuswe, oku kuthetha ukuba akukho i-corpus luteum eyasala emva ukuvelisa i-progesterone efunekayo ukuxhasa i-uterine bining for the pregnancy. Yingakho kufuneka uthabathe i-progesterone ngexesha lokunyanga kwe-IVF.

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Kulinganisela

Ngenxa yobunzima benkqubo yokuzala, ngummangaliso osebenza rhoqo kaninzi njengoko wenzayo. Ngaphezu koko, asizange sithethe malunga nomntu wesibini we-equation.

Singaqalanga nokuqwalasela indlela amanye ama-hormone emzimbeni angathintela ngayo ama-hormone ozalwayo, nokuba ubudala, ubunzima kunye nezinye izinto zingathintela njani le nkqubo ephosakeleyo.

Xa ubhekisisa ngokwenene, kuyamangalisa, kwaye kum, kushukumisela ingqondo ebalulekileyo kwihlabathi esiphila kulo kunye nezinto ezininzi ezithathayo.

Funda ngakumbi inkqubo yakho yokuzala:

• Indlela Yokufumana Isibeleko: Kubaqalayo
• Izinto Zonke Umntu Omele Ukwazi Ngobubele (Nangona kulungile ukuba abafazi bazi le nto, nabo!)
• Izinto Zonke Umfazi Omnye Ufuna Ukwazi Ngobubele (Nangona kukulungile ukuba amadoda azi ezi zinto, nazo!)
• Amanyathelo Asebenzayo Ukutya Okulungileyo Nokunyuka Okunye
• I-Folic Acid yoLuntu
• Ngaba Kukho Iidlo Ezikhethekileyo Zokunceda Ukunyusa?
• Iingcebiso ezili-10 zokunyusa ukwanda komntu
• Iimpawu ezimbi zokudiliza ukuphucula ukuzala
• I-Mind-Body Treatment for Fertility

_Imithombo:

_{UFalker, u-Elizabeth Swire. (2004). Incwadana yokuPhucula iNgeniso . I-United States yaseMerika: Iincwadi ze-Riverhead.}

_{UGrene, uRobert A. noTarken, uLaurie. (2008). IHormone egqibeleleyo Ukulinganisa Ukunyusa . I-United States yaseMelika: I-Press Rivers.}

_{Speroff, L, i-Glass, RH, iKase, NG. (1999) I- Endocrinology ye-Clinical Gynecologic ne-Infertility, i-6th edition. United States of America: uLippincott Williams & Wilkins.}