Ukuqonda Izinga eliphezulu zeTesttosterone eMadodeni nakwaBasetyhini

by URachel Gurevich; Ukuhlaziywa ngu-Anita Sadaty, MD

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Izinga leTesttosterone kuMadoda nakwabaseThini Xa i-TTC

I-Testosterone ibalulekile ekuveliseni kunye nokuphila ngokubanzi kumadoda kunye nabasetyhini. Amanqanaba aphantsi angabangela ukukhathala kwabo bobabini. UCharles Knox / Getty Images

Uvavanyo lwezinga leTesttosterone liyinxalenye ebalulekileyo yolu vavanyo lokuvuna. Nangona i-testosterone idlalwa ngokuba yi-hormone "yindoda", i-testosterone ibalulekile kwimpilo yesilisa neyesetyhini.

Kodwa, njengama-hormone, awufuni nto encinci okanye kakhulu.

Kwamadoda, i-testosterone ephantsi yinto ebangela ukuba kungabikho ntsholongwane. Nangona kunjalo, usenokumangaliswa ukuva ukuba amazinga aphezulu aphezulu e-testosterone ayingxaki.

Kubasetyhini, amanqanaba aphezulu e-testosterone angabonisa ingxaki yokuzala. Abasetyhini banokuba namazinga aphantsi e-testosterone, kodwa oku kuvela emva kokuphuma kwindoda kwaye kungekhona ngokuqhelekileyo ngexesha lokubeletha.

Yintoni eyenza amazinga aphezulu aphantsi okanye aphantsi e-testosterone kumadoda nabasetyhini? Ngaphezu koko, yintoni enokuyenza malunga nayo, ingakumbi ukuba uzama ukukhulelwa?

Qhubeka ufunda. Okokuqala, makhe sixoxe ngamanqanaba aphantsi e-testosterone kumadoda, awaziwa ngokuba yi-hypogonadism yesilisa. A

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Iimpawu zeNqanaba elisezantsi leTesttosterone kuMadoda

I-libido ephantsi kunye ne-erectile i-dysfunction zibonakalisa iimpawu zamanqanaba aphantsi e-testosterone. Umthombo wesithombe / i-Getty Izithombe

I-testosterone ephantsi iyaziwa ngokuba yi-hypogonadism yesilisa. I-hypogonadism yamadoda ingabangela ukungabikho.

Ugqirha wakho unokucinga ukuba amanqanaba e testosterone aphantsi kakhulu ukuba ...

Amazinga akho e-Testosterone yamahhala angaphantsi kwe-9 ng / dL
Izithamo zakho zeTesttosterone ziphantsi kwama-240 ng / dL

Iimpawu ze-testosterone ephantsi kumadoda ingaquka ...

Ukungenzi lutho
Ukuxinezeleka
Ukukhathala
Ukunciphisa ubunzima besisu
Ukukhula kweendvuba kunye nokukhula kweenwele zomzimba
Ukulala ngesondo
Ukungasebenzi kwe-Erectile
Amabele abanzi
Amandla aphantsi
Ukutshisa okushisayo
Ingxaki noxinzelelo

I-hypogonadism yamadoda oyintloko xa ixinzelelo luvela kwiimvavanyo. Oku kungabuye kuhanjiswe njengokungaphumeleli kokuqala kweetestular okanye ukuphela komntu wesilisa. Enyanisweni, ezinye zeempawu zifana nokuqhathaniswa kwamadoda.

I-hypogonadism yesibini yindoda yinkxalabo ephuma kwi-pituitary gland okanye hypothalamus. Ezi zengqungquthela kwindawo yengqondo zivelisa i-hormones ye-FSH ne- LH , ebonisa ukuba iimvavanyo zivelisa i-testosterone.

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Izizathu zeTesttosterone ephantsi kwiMadoda

Ukunyaniseka xa kunesizathu esinqandekayo se-testosterone kumadoda kwaye sinokuba nomphumo onamandla kunokuguga. UDavid Zaitz / Getty Images

Ezinye izimbangela zezinga eliphantsi le testosterone kumadoda ziquka ...

Ubudala : Xa amadoda efikelela kuma-50 ubudala, amazinga e-testosterone aqala ukuhla kwezemvelo. Ukuzala komntu kuyancipha ngokudala , nangona kungenjalo njengokuba kunjalo nakwabasetyhini.

Ubutyebi : Ubutyebi bungaba nomthelela omkhulu kumanqanaba e testosterone kuneminyaka yobudala. Uphando lufumene ukuba ukwanda kwamanani kuhambelana ngqo nokunciphisa amanqanaba e-testosterone. Ukulahlekelwa isisindo kunokubuyisela amanqanaba akho e-testosterone.

Ukutshaya : Ukubhema kwandisa ingozi yokuntula abantwana .

Ukuba ngaphantsi komzimba : Amanqanaba angabonakaliyo aphantsi kwe-BMI, ukungondleki, kunye nokuzivocavoca ngokweqile kungaholela kumazinga aphantsi e-testosterone kunye nokunciphisa ukuzala.

I-Klinefelter syndrome (KS) (XXY) : Le ngxaki yesifo somzimba apho kunokuba ibe ne-X kunye ne-Y ye-chromosome enye, indoda ine-X eyongezelelweyo ye-chromosome. Yisona sizathu esiqhelekileyo sokusweleka kwesintu.

I-Kallmann syndrome : Yiyo imeko yezofuzo apho ukuphela komntwana kungaphumeleli ukuqala okanye kungagqibekanga.

Iziphazamiso zengqondo : oku kubandakanya iingxaki malunga nokusebenza kwepituitary. Kungaba ngumphumo wesifo sokuxhamla okanye isisu seengqondo. Okanye, unyango lwe-tumor ye-brain kunye ne-radiation lunokubangela umonakalo omde we-pituitary.

Amathambo angapheliyo : oku kudla ngokusombulula ngexesha lokuqala kwasebuntwaneni. Ukuba akunjalo, kunjalo, kufuneka ilungiswe. Ngaphandle koko, kunokubangela iingxaki ze-hormone kamva ebomini.

Amanqanaba aphezulu angaqhelekanga : Le yaziwa nangokuthi i-hemochromatosis.

Ukulimala kobufakazi : Ukuba kukho enye i-testicular eyalimala, ukuveliswa kwe testosterone kunokuqhelekileyo.

Unyango lwe-Cancer : I-Chemotherapy kunye neyeza zonyango zingenza i-testosterone iphantsi kwaye ibenciphise umveliso wesilisa. Nangona kunjalo, ngamanye amaxesha umonakalo unaphakade. Olunye uphando lwafumanisa ukuba ama-30% wamadoda afumana amanqanaba aphantsi e-testosterone emva kokunyanga.

I-HIV / AID : intsholongwane inokuphazamisa indlela iimvavanyo, i-pituitary kunye ne-hypothalamus. Oku, kungakhokelela kumanqanaba aphantsi ase testosterone.

Ugula okanye utyando olukhulu : Oku kuza kuguqula ngokwayo emva kwexesha lokubuyisela. Ezinye izifo, njengama-mumps, zingabangela iingxaki ze-hormonal ezide.

Ukusetyenziswa kweziyobisi okanye ukonwabisa : Ngokomzekelo, inambuzane ingabangela amanqanaba aphantsi e-testosterone.

Amanqanaba aphezulu kakhulu oxinzelelo : Amanqanaba aphezulu e-hormone ye-cortisol edibeneyo ahlanganiswe namazinga aphantsi e-testosterone.

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Ukunyanga izinga leTesttosterone elisezantsi kwiMadoda

Ugqirha wakho unokunika i-testosterone engenayo ukukhulisa amanqanaba akho kunye nokuzala kwakho. Tom Merton / Getty Izithombe

Ukuba amanqanaba akho aphantsi e-testosterone yiphumo lesimo sengqondo okanye imeko yokuphila (njengento yokukhuluphala), ngoko ubuncinane inxalenye yesicwangciso sakho soonyango iya kunyanga imeko.

Kungenzeka ukuba kula maxesha ukuba amanqanaba e-testosterone abuyele kumazinga aqhelekileyo emva kokuba unyango okanye ukuguquka kwendlela yokuphila.

Le nto ayisoloko inokukhetha, ngelanga.

Kule meko, ugqirha wakho unokuncoma enye, enye, okanye zonke ezi zilandelayo:

I-Testosterone supplementation : Ugqirha wakho unokunika i-testosterone engenayo. Oku kuya kuba nethemba lokukhulisa umveliso wesilisa.

I-Testosterone supplementation inokumiselwa kwakhona ukuphucula impilo yakho kunye nempilo jikelele, nokuba ngaba ayiyi kusombulula ingxaki yokuzala.

I-Clomid : Nangona ininzi idla ngokuxhatshazwa kwabantwana besifazane, iClomid ingasetyenziselwa amadoda ukukhuthaza amanqanaba e-testosterone.

Ukwelashwa kwe-IVF : I- IVF ingasetyenziswa kunye okanye endaweni yokuxhaswa kwe-hormonal.

Ukuba kukho iziganeko zokuzala ezibandakanyekayo, ugqirha wakho unokuncoma nokuba uzame i-IVF kuqala.

I-IVF ne-ICSI : Nge- IVF-ICSI , isityalo esisodwa singeniswe ngqo kwiqanda.

Ukuqalwa kwamabhontsi esisiseko (TESE) : Ukuba isibalo esiphantsi sembewu okanye ubuninzi besibalo singumngeni , ugqirha wakho unokubonisa ubungqina bentermular (TESE) . Oku kubandakanya ukufumana isisu ngokuthe ngqo kwii-testes nge-biopsy.

Umnikezeli wesidoda : Kwezinye iimeko, ugqirha wakho unokuncoma usebenzisa umniki wesilisa.

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Iimpawu kunye neengxaki zeeNqanaba eziPhakamileyo zeTesttosterone kuMadoda

Amanqanaba e-testosterone aphakamileyo angakhokelela ekungciphekweni kokuziphatha. ftwitty / Getty Izithombe

Amanqanaba eeprotestone aphezulu aqhelekanga ayaziwa nangokuthi i-hypergonadism.

Ugqirha wakho unokucinga ukuba amanqanaba e testosterone aphezulu kakhulu ukuba ...

Amanqanaba akho aphelele ase testosterone angaphezu kwe-950 ng / dL
Amazinga akho e-testosterone ekhululekile angaphezu kwama-30 ng / dL

Iimpawu kunye neempawu ze testosterone ephezulu ziquka ...

Ubusana bokuqala, kumadoda aselula
Ukungabikho kokunciphisa nokunciphisa isibalo sembewu
Acne
High libido
"Uboya"
Igazi elonyukayo
Ubomvu obomvu obuninzi
Ukuziphatha okunyusa ingozi
Inkcaso

Amanqanaba aphezulu angabonakaliyo angabangela ukuba ...

Iimvumba: Izicubu ze-Adrenal kunye neet testicular zingabangela i-testosterone ephezulu ngokungavamile.
Ukusetyenziswa kakubi kwe-antibolic steroid: ngamanye amaxesha asetyenziswa ngabadlali kunye nabakhi bomzimba ukwakha ubuninzi bemisipha okanye ukunyusa ukusebenza kwezemidlalo. Abanye abagijimi bathatha iClomid ukukhulisa ukusebenza, ngokungekho mthethweni.
Ukuxhaswa kweTesttosterone: Ngamanye amaxesha umiselwe ngugqirha, kwaye ngamanye amaxesha athengwa ngokungemthetho ngaphandle kwemithi.
Ukudibanisa nomntu osebenzisa i-gel testosterone. I-gel ingasuswa ngengozi kumnye umntu, ukuphakamisa amanqanaba e-testosterone ngokungazi.

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UkuPhatha amaNqanaba eTesttosterone aphezulu ngokungapheliyo kuMadoda

Unokucinga ukuba i-testosterone enye ithetha ukuzala okuphezulu, kodwa ayisebenzi njengaleyo. UPeter Dazeley / Getty Images

Kuyinto engavamile ukuba amanqanaba e testosterone aphakanyiswe kakhulu angabangela ukungabikho kwamadoda. Nangona kunjalo, ukuba amanqanaba aphezulu kakhulu, umbuzo uya kuba ngaba ubangelwa yi-tumor (engaqhelekanga) okanye ngokusetyenziswa kweziyobisi.

Ukuba kungenxa yokusebenzisa i-anabolic steroid okanye ukuxhaswa kwe-testosterone, ukuxhaswa kwi-supplement okanye i-steroids kufuneka kulungiswe ingxaki. Oku kufanele kwenziwe phantsi kolawulo lugqirha.

Kuyamangalisa amadoda amaninzi ukuba i-testosterone ephakamileyo ingabangela ukungabikho. Amanye amadoda athabatha izongezelo ze testosterone zicinga ukuba ziya kuphucula ukuzala kwazo. Okanye, bathabatha ithemba lokuphucula amandla abo, amandla kunye namanqanaba emandla.

Ngelishwa, ukuxhaswa kwe-testosterone kumadoda angayifuni emzimbeni kungabangela ukungabikho.

Olunye uphando lwafumanisa ukuba ngamadoda athatha izongezo ze testosterone kwaye ayengazidingi, i-88.4% yayingu-azoospermic. Ngamanye amazwi, abazange bavelise nantoni na.

Nangona kunjalo, emva kweenyanga ezintandathu emva kokumisa i-testosterone supplementation, i-65% yamadoda yayingekho i-azoospermic. Baqala ukuvelisa isidoda kwakhona.

Amadoda ayenaye kuphela afuna ukukhathazeka ngamanqanaba e-testosterone.

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Izinga leTesttosterone ephakamileyo kunye neNcinci kumaBhinqa

Abasetyhini abanamazinga aphezulu e-testosterone banokubona ukukhula kwesikhumba, ubuso obunokuba buhlungu. Westend61 / Getty Izithombe

Xa kuziwa ekuzameni ukukhulelwa, kubafazi, i-testosterone ephakamileyo ngokuqhelekileyo ingxaki kune testosterone ephantsi.

I-Testosterone ingenye yeehomoni ezininzi ezibizwa ngokuba yi-androgens. Amanqanaba aphezulu e-androgen aziwa ngokuba yi-hyperandrogenism.

Iimpawu zezinga eliphezulu ze-androgen ziquka ...

Ixesha elingavumelekanga
Ukugcoba
Acne
Ukukhula kweenwele ezingavamile
Ukulinganisa umzekelo wesilisa
Izwi elomelezayo
Ukwanda kobunzima besisu
I-clitoris ekhulisiweyo

Izizathu ezinokwenzeka zezinga eliphezulu ze testosterone kubasetyhini ziquka:

I-PCOS: I- Polycystic i-ovarian syndrome yimbangela eqhelekileyo yokungabikho kwabantwana abasetyhini. I-PCOS inxulumene nokukhuluphala nokuxhatshazwa kwe-insulin.
I-congenital adrenal hyperplasia (CAH): Lo mfuzo wezofuzo ophazamisa izigulane zakho ze-adrenal ukuvelisa ama-hormone afunekayo. Kungabangela ukungabikho kwamandla kwindoda kunye nabasetyhini. Abanye abafazi baya kufunyaniswa njengabantwana. Kwezinye izihlandlo, kunokuthi kwenzeke kamva ebomini. Oku kwaziwa ngokuba yi-late-stance okanye i-congenital adrenal hyperplasia (CAH).
I-adrenal okanye i-ovarian cancers: amanqanaba aphezulu e-testosterone angaphezulu kwama-200 ng / dL angabonwa kwiimeko zomhlaza.
Usetyenziso lwe-Anabolic Steroid: Abadlali bezemidlalo abayena kuphela abasebenzisa kakubi i-steroids ukuphucula ukusebenza. Abasetyhini abasebenzisa kakubi i-steroids bangaba namanqanaba aphezulu angamaphepha ka-testosterone.

Kuthiwani nge-testosterone ephantsi kubafazi?

Abafazi abanamaqondo aphantsi ase testosterone banokuva ...

Libido ephantsi
Ukuxinezeleka
Ukukhathala
Ubunzima beCognitive

I-testosterone ephantsi kubasetyhini ibonakala ngokugqithiseleyo ngexesha lokuyeka ukuphuma komzimba, nokuba ingaba naliphi na iminyaka. Amanqanaba aseTesttosterone ayancipha kunye ne-estrogen kunye nezinye i-hormone zokuzala. I-testosterone ephantsi ayisoloko iyingxaki kubasetyhini abazama ukukhulelwa.

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UkuPhatha amaNqanaba eSettosterone angavumelekanga kwabesetyhini

Ukuzivocavoca, ukutya kunye nokulahlekelwa kwesisindo kunokunceda ukunciphisa amanqanaba e-testosterone, ingakumbi ngoncedo lwe-metformin. Cultura RM / JPM / Getty Izithombe

Xa uphatha amanqanaba aphezulu e-testosterone, ugqirha wakho uya kujonga iinjongo zakho kunye neempawu zakho. Unyango uhlukile uma uzama ukukhulelwa.

Ngokomzekelo, enye inokwenzeka ukuba unyango luyimpilisi yolawulo lokuzalwa , kodwa loo nto ayifanelekile kumntu ozama ukukhulelwa.

Enye inokwenzeka ukuba i-spironolactone (i-brand name Aldactone.) I-spironolactone ayikhuselekile ukuthatha xa ikhulelwe, ngoko akufanelekile abo bazama ukukhulelwa.

Izinketho kubafazi abanethemba lokuba nomntwana ziquka:

Ukulahlekelwa kwesisindo kunye nokuzivocavoca : Ukulahlekelwa ubunzima obuninzi nokuzivocavoca rhoqo, ngokukodwa kubasetyhini abane-PCOS, kunokuncedisa amanqanaba e-testosterone kwaye unokuqalisa ukuqala.

I-Metformin : Ukunyanga ukuxhatshazwa kwe-insulin nesifo se-diabetes ye- metformin kunokuncedisa ukunciphisa iimpawu ze-PCOS kunye nokuqalisa kwakhona i-ovulation.

Amachiza enobungozi : Uyakudinga ukuba utshintsho lwezinto zobomi kunye neziyobisi zokuzala. I-Clomid kunye ne- letrozole yile ndlela yokuqala yokunyanga kwenzalo yabasetyhini abane-PCOS.

Izonyango zokuphunga izifo : Kwabesetyhini abazama ukukhulelwa, unyango lwezonyango ezinjengekwenkcenkceshelo okanye ukutyhulwa izixazululo ezinokwenzeka ukukhula kweenwele ezingafunekiyo.

Indlela Yokufumana Isibeleko ngePCOS

Emininzi kwizizathu zokungabikho komntwana:

_Imithombo:

_{Camacho EM1, Huhtaniemi IT, O'Neill TW, Finn JD, Pye SR, Lee DM, Tajar A, Bartfai G, Boonen S, Casanueva FF, Forti G, Giwercman A, Han TS, Kula K, Keevil B, Pendleton N, Punab M, Vanderschueren D, iWu FC;} _{Iqela le-EMAS.} _{Utshintsho olunexesha elidala kwimisebenzi ye-hypothalamic-pituitary-testicular kumadoda aphakathi kwamadala kunye namadoda amadala aguqulwa ngokunyuka kwesisindo kunye nezinto zokuphila: iziphumo ezide ezivela kwisiFundo se-Aging yase-Yurophu. "I-Eur J Endocrinol.} _{2013 Feb 20; 168 (3): 445-55.} _{i-doi: 10.1530 / i-EJE-12-0890.} _{Print 2013 Mar. http://eje-online.org/content/168/3/445.long}

_{Cumming DC, Quigley ME, Yen SS.} _{"Ukunciphisa ngokugqithiseleyo ukujikeleza kwamanqanaba e testosterone nge-cortisol kumadoda." J Clin Endocrinol Metab.} _{1983 Sep; 57 (3): 671-3.} _{http://www.ncbi.nlm.nih.gov/pubmed/6348068/}

_{Groth KA1, Skakkebæk A, Høst C, Gravholt CH, Bojesen A. "Ukuphononongwa ngonyango: I-Klinefelter syndrome - ukuhlaziywa kwekliniki." J Clin Endocrinol Metab.} _{2013 Jan; 98 (1): 20-30.} _{i-doi: 10.1210 / jc.2012-2382.} _{I-Epub 2012 Nov 1. http://www.ncbi.nlm.nih.gov/pubmed/23118429/}

_{Howell SJ1, Radford JA, Ryder WD, uShalet SM.} _{Umsebenzi weTeticular emva kwe-cytotoxic chemotherapy: ubungqina bee-cell ze-Leydig. "J Clin Oncol.} _{Ngo-Meyi ka-1999; 17 (5): 1493-8.} _{http://www.ncbi.nlm.nih.gov/pubmed/10334536/}

_{Høst C, Skakkebæk A, Groth KA, Bojesen.} _{"Indima ye-hypogonadism kwi-Klinefelter syndrome." I-Asia J Androl.} _{2014 ngoMatshi-Apr; 16 (2): 185-91.} _{i-doi: 10.4103 / 1008-682X.122201.} _A1. _{http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955327/}

_{Kumar P, Kumar N, Thakur DS, Patidar A. I-hypogonadism yamadoda: Izimpawu kunye noonyango.} _{Umbhalo woPhuhliso lwezoPhando lweeMveliso zobuGcisa noPhando .} _{2010; 1 (3): 297-301.} _{i-doi: 10.4103 / 0110-5558.72420.} _{http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255409/}

_{I-Surampudi P1, iSwerdloff RS, Wang C. "Ukuhlaziywa kwonyango lwama-hypogonadism wesilisa." Ingcali ye-Opin Pharmacother.} _{2014 Juni; 15 (9): 1247-64.} _{i-doi: 10.1517 / 14656566.2014.913022.} _{Epub 2014 Apr 23. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168024/}

_{I-Testosterone: Ulwazi lweziyobisi.} _{Lexicomp, Inc. UptoDate.com.} _{Ufikelele kuSeptemba 9, 2015. http://www.uptodate.com/contents/testosterone-drug-information}

_{I-ID yovavanyo: TGRP;} _{I-Testosterone, i-Total kunye ne-Free, i-Serum.} _{IiMayoClinic zeZonyango zonyango.} _{Ufikelele kuSeptemba 9, 2015. http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interprective/8508}

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